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Subunit: Component of the large ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S) Developmental stage: Down-regulated during adipocyte, kidney, and heart differentiation Sequence caution: Sequence=AAB22173.1; Type=Frameshift; Positions=124; Sequence=CAM45852.1; Type=Erroneous gene model prediction; Sequence=CAM45853.1; Type=Erroneous gene model prediction; 1 PDB 3D structure from [IMAGE] and Proteopedia [IMAGE] for RPL10: 2PA2 (3D) [IMAGE]
Function: Genatlas biochemistry entry for RPL10: 60S ribosomal protein L10 Gene Ontology (GO): 3 molecular function terms: About this table GO ID Qualified GO term Evidence PubMed IDs GO:0003735 structural constituent of ribosome NAS 12962325 GO:0005515 protein binding IPI 16741966 GO:0044822 poly(A) RNA binding IDA -- [IMAGE] Find genes that share ontologies with RPL10 About GenesLikeMe Phenotypes: 4 GenomeRNAi human phenotypes for RPL10: Decreased G3BP1 protein expres Increased G2M DNA content Nuclear 60S biogenesis defects Nucleoplasmic pre-40S maturati Animal Models: [IMAGE] inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RPL10 [IMAGE] inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for RPL10 [IMAGE] genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RPL10 [IMAGE] genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RPL10 miRNA Products: miRTarBase miRNAs that target RPL10: hsa-let-7e-5p (MIRT051433), hsa-mir-324-3p (MIRT042981), hsa-mir-195-5p (MIRT044868), hsa-mir-423-5p (MIRT038172), hsa-mir-505-5p (MIRT037945), hsa-mir-504-5p (MIRT041089), hsa-mir-744-5p (MIRT037586), hsa-mir-100-5p (MIRT048579), hsa-mir-22-5p (MIRT038962), hsa-mir-16-5p (MIRT031375) [IMAGE] Block miRNA regulation of human, mouse, rat RPL10 using miScript Target Protectors [IMAGE] Search for qRT-PCR Assays for microRNAs that regulate RPL10 [IMAGE] SwitchGear 3'UTR luciferase reporter plasmid: RPL10 3' UTR sequence Inhib. RNA Products: [IMAGE] OriGene RNAi products in human, mouse, rat for RPL10 [IMAGE] Predesigned siRNA for gene silencing in human, mouse, rat RPL10 Gene Editing Products: [IMAGE] DNA2.0 Custom Protein Engineering Service for RPL10 Clone Products: [IMAGE] OriGene clones in human, mouse for RPL10 (see all 6) OriGene ORF clones in mouse, rat for RPL10 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling [IMAGE] GenScript: all cDNA clones in your preferred vector: RPL10 (NM_007104) [IMAGE] Sino Biological Human cDNA Clone for RPL10 [IMAGE] DNA2.0 Custom Codon Optimized Gene Synthesis Service for RPL10 [IMAGE] Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPL10 Cell Line Products: [IMAGE] GenScript Custom overexpressing Cell Line Services for RPL10 [IMAGE] Browse ESI BIO Cell Lines and PureStem Progenitors for RPL10 [IMAGE] In Situ Assay Products: [IMAGE] Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPL10 Flow Cytometry Products: [IMAGE] eBioscience FlowRNA Probe Sets (VA1-12078) for RPL10 [IMAGE]
Similarity: Belongs to the ribosomal protein L10e family [IMAGE]
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