Gene content    
SKIIP (approved by HUGO)
SNW domain containing 1
Other
Bx42
MGC119379
NCOA-62
NCoA-62
PRPF45
Prp45
SKIIP
SKIP
NCBI: 14q24.3    Ensembl: 14q24.3
SNW1_HUMANSize: 536 amino acidsMass: 61494 Da

  • Subcellular location: Nucleus
  • Subunit: Interacts with the ski oncogene. Can be found in spliceosomes, but may also associate with non-spliceosomal proteins
  • Function:
    Involved in vitamin D-mediated transcription. Can function as a splicing factor in pre-mRNA splicing
  • Similarity:
    Belongs to the SNW family.
  • Protein Domain/Family    
    Source ID Domain Name Type
    InterProIPR004015SKIP_SNWSKIP/SNWDomain
    BlocksIPB004015SKIP/SNW domainSKIP/SNW domain

    Gene Ontology    
    Type Term Evidence Source Pub
    Biological Process Notch binding IPI GOA PubMed
    nucleus TAS GOA PubMed
    protein binding IPI GOA PubMed
    Cellular Component spliceosome complex IDA GOA PubMed
    transcription coactivator activity TAS GOA PubMed
    Molecular Function negative regulation of transcription IDA GOA PubMed
    nuclear mRNA splicing, via spliceosome IDA GOA PubMed
    regulation of transcription from RNA polymerase II promoter TAS GOA PubMed

    SKIIP cross reference    
    PubMed OMIM Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene