Gene content
Symbol	SLC6A3 (-- by HUGO)
Name	solute carrier family 6 (neurotransmitter transporter, dopamine),... -------------------------------
Category	--
Alias	Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3 DA Transporter DAT1 PKDYS DAT Sodium-Dependent Dopamine Transporter Solute Carrier Family 6 Member
Cytogenetic band	NCBI: 5p15.3    Ensembl: 5p15.33
Protein information	SC6A3_HUMAN Size: 620 amino acids Mass: 68495 Da Subcellular location: Membrane; Multi-pass membrane protein Miscellaneous: This protein is the target of psychomotor stimulants such as amphetamines or cocaine Secondary accessions: A2RUN4 Q14996 Explore the universe of human proteins at neXtProt for SLC6A3: NX_Q01959 Post-tra Subunit: Homooligomer; disulfide-linked. Interacts with PRKCABP and TGFB1I1. Interacts (via N-terminus) with SYNGR3 (via N-terminus) (By similarity). Interacts with SLC18A2 (By similarity) Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A3 subfamily

Protein Domain/Family
Source	ID	Domain	Name	Type
InterPro	IPR000175	Na/ntran_symport	Sodium:neurotransmitter symporter	Family
	IPR002436	Na/ntran_symport_dopamine	Dopamine neurotransmitter transporter	Family
Blocks	IPB002436	Dopamine neurotransmitter transporter signature	Dopamine neurotransmitter transporter signature

Disorder & Mutation
Source	Disease
SWISS-PROT	Defects in SLC6A3 are the cause of parkinsonism-dystonia infantile (PKDYS) [MIM:613135]. A neurodegenerative disorder characterized by infantile onset of parkinsonism and dystonia. Other neurologic features include global developmental delay, bradikinesia and pyramidal tract signs

SLC6A3 cross reference
PubMed Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene