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Subunit: Belongs to the RNA polymerase II (Pol II) transcriptional multiprotein complex, together with the TATA-binding protein (TBP) and other TBP-associated factors (TAF(II)s). Binds SF1
Tissue specificity: Ubiquitous. Observed in all fetal and adult tissues [IMAGE] Custom PCR Arrays for TAF15 Primer Products: [IMAGE] OriGene qSTAR qPCR primer pairs in human, mouse for TAF15 [IMAGE] Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TAF15 [IMAGE] Quant
Function: UniProtKB/Swiss-Prot Summary: RBP56_HUMAN, Q92804 Function: RNA and ssDNA-binding protein that may play specific roles during transcription initiation at distinct promoters. Can enter the preinitiation complex together with the RNA polymerase II (Pol II) Gene Ontology (GO): Selected molecular function terms (see all 7): About this table GO ID Qualified GO term Evidence PubMed IDs GO:0000166 nucleotide binding IEA -- GO:0003676 nucleic acid binding -- -- GO:0003677 DNA binding IEA -- GO:0003723 RNA binding -- -- GO:0005515 protein binding IPI 19124016 [IMAGE] Find genes that share ontologies with TAF15 About GenesLikeMe Phenotypes: 3 GenomeRNAi human phenotypes for TAF15: Decreased cell number, increas Decreased viability of wild-ty Synthetic lethal with Ras Animal Models: [IMAGE] inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TAF15 [IMAGE] inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TAF15 [IMAGE] genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TAF15 [IMAGE] genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TAF15 miRNA Products: miRTarBase miRNAs that target TAF15: hsa-mir-125b-5p (MIRT046039), hsa-mir-196a-5p (MIRT048160), hsa-mir-320a (MIRT044517), hsa-mir-132-3p (MIRT021732), hsa-mir-181a-5p (MIRT025067), hsa-mir-24-3p (MIRT030412), hsa-mir-16-5p (MIRT031463), hsa-mir-615-3p (MIRT040091), hsa-mir-501-5p (MIRT041143), hsa-mir-10a-5p (MIRT047604), hsa-mir-877-3p (MIRT037061) [IMAGE] Block miRNA regulation of human, mouse, rat TAF15 using miScript Target Protectors [IMAGE] Selected qRT-PCR Assays for microRNAs that regulate TAF15 (see all 26): hsa-miR-3128 hsa-miR-16-2* hsa-miR-137 hsa-miR-15a hsa-miR-25 hsa-miR-1271 hsa-miR-1260b hsa-miR-16-1* [IMAGE] SwitchGear 3'UTR luciferase reporter plasmid: TAF15 3' UTR sequence Inhib. RNA Products: [IMAGE] OriGene RNAi products in human, mouse, rat for TAF15 [IMAGE] Predesigned siRNA for gene silencing in human, mouse, rat TAF15 Gene Editing Products: [IMAGE] DNA2.0 Custom Protein Engineering Service for TAF15 Clone Products: [IMAGE] OriGene clones in human, mouse for TAF15 (see all 11) OriGene ORF clones in mouse, rat for TAF15 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling [IMAGE] GenScript: all cDNA clones in your preferred vector (see all 2): TAF15 (NM_139215) [IMAGE] Browse Sino Biological Human cDNA Clones [IMAGE] DNA2.0 Custom Codon Optimized Gene Synthesis Service for TAF15 [IMAGE] Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TAF15 [IMAGE] Addgene plasmids for TAF15 [IMAGE] Cell Line Products: [IMAGE] GenScript Custom overexpressing Cell Line Services for TAF15 [IMAGE] Browse ESI BIO Cell Lines and PureStem Progenitors for TAF15 [IMAGE] In Situ Assay Products: [IMAGE] Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TAF15
Similarity: Belongs to the RRM TET family Contains 1 RanBP2-type zinc finger Contains 1 RRM (RNA recognition motif) domain [IMAGE]
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