Gene content    
TAL2 ( by HUGO)
T-Cell Acute Lymphocytic Leukemia
Other
T-Cell Acute Lymphocytic Leukemia 2
Class A Basic Helix-Loop-Helix Protein 19
TAL-2
T-Cell Acute Lymphocytic Leukemia Protein 2
BHLHA19
bHLHa19
NCBI: 9q32    Ensembl: 9q31.2
TAL2_HUMANSize: 108 amino acidsMass: 12291 Da

  • Function:
    Genatlas biochemistry entry for TAL2: helix loop helix protein,homologous to TAL1,involved in T cell acute lymphoblastic leukemia,with translocation t(7;9)(q35;q34) Gene Ontology (GO): 2 molecular function terms: About this table GO ID Qualified GO term Evidence PubMed IDs GO:0003677 DNA binding IEA -- GO:0046983 protein dimerization activity IEA -- [IMAGE] Find genes that share ontologies with TAL2 About GenesLikeMe Phenotypes:
  • Similarity:
    Contains 1 bHLH (basic helix-loop-helix) domain [IMAGE]

    • Protein Domain/Family    
    Source ID Domain Name Type
    InterProIPR011598bHLH_domHelix-loop-helix DNA-bindingDomain
    BlocksIPB001092Basic helix-loop-helix dimerization domain bHLHBasic helix-loop-helix dimerization domain bHLH

    Disorder & Mutation    
    Source Disease
    Genatlasacute lymphoblastic leukemia (T cell) with breakpoint in t(7;9)(q35;q34) translocation
    SWISS-PROTNote=A chromosomal aberration involving TAL2 may be a cause of some T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(7;9)(q34;q32) with TCRB

    TAL2 cross reference    
    PubMed OMIM Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene