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Subcellular location: Nucleus. Cytoplasm (By similarity). Note=Shuttles between nucleus and cytoplasm
Subunit: Interacts with phosphorylated CSF1R and THOC1 (By similarity). Component of the THO complex, which is composed of THOC1, THOC2, THOC5, THOC6 and THOC7. Together with THOC3, ALYREF/THOC4 and DDX39B, THO forms the transcription/export (TREX) complex. Interacts with ALYREF/THOC4 and THOC7. Interacts (via N-terminus) with the NTF2 domain of NXF1. Forms a complex with CEBPB (By similarity)
Tissue specificity: Ubiquitously expressed
Similarity: Belongs to the THOC5 family
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