Gene content  |
| TLX1 ( by HUGO) |
| T-Cell Leukemia Homeobox 1 |
| Oncogene |
| T-Cell Leukemia Homeobox 1 HOX11 TCL3 Homeobox Protein Hox-11 Proto-Oncogene TCL-3 T-Cell Leukemia/Lymphoma Protein 3 Homeo Box 11 (T-Cell Lymphoma 3-Associated Breakpoint) Homeo Box-11 (T-Cell Leukemia-3 Associated Breakpoint Homologous To Drosophila Notch) T-Cell Leukemia Homeobox 1 Homeo Box-11 (T-Cell Leukemia-3 Associated Breakpoint Homologous To Drosophila Notch) T-Cell Leukemia Homeobox Protein 1 |
| NCBI: 10q24 Ensembl: 10q24.31 |
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Subunit: Interacts with MEIS1, MEIS2, PBX1, PBX2 and PBX3 Miscellaneous: TLX1 is oriented in a head-to-head manner with TDI. Both genes share the same promoter with robust bidirectional activity
Function: UniProtKB/Swiss-Prot Summary: TLX1_HUMAN, P31314 Function: Controls the genesis of the spleen. Binds to the DNA sequence 5'-GGCGGTAAGTGG-3' Gene Ontology (GO): 5 molecular function terms: About this table GO ID Qualified GO term Evidence PubMed IDs GO:0003677 DNA binding -- -- GO:0003700 sequence-specific DNA binding transcription factor activity IEA -- GO:0005515 protein binding IPI 19559479 GO:0043565 sequence-specific DNA binding IEA -- GO:0046982 protein heterodimerization activity IEA -- [IMAGE] Find genes that share ontologies with TLX1 About GenesLikeMe Phenotypes:
Similarity: Contains 1 homeobox DNA-binding domain [IMAGE]
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