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Subunit: Forms a homodimer or heterodimer with other members of the family. All isoforms interact with several 14-3-3 proteins Developmental stage: Isoform 2 is expressed at lower levels in fetal brain and kidney than in adult brain and kidney Sequence caution: Sequence=BAD97351.1; Type=Erroneous initiation;
Tissue specificity: Isoform 2 is expressed in colon, breast, prostate, pancreas and kidney tumor cell lines. Isoform 2 is expressed at high levels in kidney, prostate, brain, small intestine and pancreas, at moderate levels in placenta and colon, at low levels in lung, liver
Function: Genatlas biochemistry entry for TPD52: tumor protein D52,breast carcinoma associated Gene Ontology (GO): 4 molecular function terms: About this table GO ID Qualified GO term Evidence PubMed IDs GO:0005509 calcium ion binding IDA 15576473 GO:0005515 protein binding IPI 12963375 GO:0042803 protein homodimerization activity IDA 9484778 GO:0046982 protein heterodimerization activity IDA 9484778 [IMAGE] Find genes that share ontologies with TPD52 About GenesLikeMe Animal Models: [IMAGE] inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TPD52 [IMAGE] inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TPD52 [IMAGE] genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TPD52 [IMAGE] genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TPD52 miRNA Products: miRTarBase miRNAs that target TPD52: hsa-mir-15b-5p (MIRT046423), hsa-mir-218-5p (MIRT024215), hsa-mir-505-3p (MIRT041053), hsa-mir-155-5p (MIRT021038), hsa-mir-103a-3p (MIRT027218), hsa-mir-34a-5p (MIRT025584) [IMAGE] Block miRNA regulation of human, mouse, rat TPD52 using miScript Target Protectors [IMAGE] Selected qRT-PCR Assays for microRNAs that regulate TPD52 (see all 52): hsa-miR-194* hsa-miR-576-3p hsa-miR-100* hsa-miR-139-5p hsa-miR-138-2* hsa-miR-218 hsa-miR-449a hsa-miR-570 [IMAGE] SwitchGear 3'UTR luciferase reporter plasmid: TPD52 3' UTR sequence Inhib. RNA Products: [IMAGE] OriGene RNAi products in human, mouse, rat for TPD52 [IMAGE] Predesigned siRNA for gene silencing in human, mouse, rat TPD52 Gene Editing Products: [IMAGE] DNA2.0 Custom Protein Engineering Service for TPD52 Clone Products: [IMAGE] OriGene clones in human, mouse for TPD52 (see all 18) OriGene ORF clones in mouse, rat for TPD52 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling [IMAGE] GenScript: all cDNA clones in your preferred vector (see all 3): TPD52 (NM_001025252) [IMAGE] Browse Sino Biological Human cDNA Clones [IMAGE] DNA2.0 Custom Codon Optimized Gene Synthesis Service for TPD52 [IMAGE] Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TPD52 Cell Line Products: [IMAGE] GenScript Custom overexpressing Cell Line Services for TPD52 [IMAGE] Browse ESI BIO Cell Lines and PureStem Progenitors for TPD52 [IMAGE] In Situ Assay Products: [IMAGE] Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TPD52
Similarity: Belongs to the TPD52 family [IMAGE]
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