Gene content    
TPD52L1 ( by HUGO)
Tumor Protein D52-Like 1
Other
Tumor Protein D52-Like 1
hD53
D53
Tumor Protein D53
NCBI: 6q22-q23    Ensembl: 6q22.31
TPD53_HUMANSize: 204 amino acidsMass: 22449 Da

  • Subunit: Forms a homodimer or heterodimer with other members of the family Sequence caution: Sequence=AAC98475.1; Type=Erroneous initiation;
  • Function:
    Genatlas biochemistry entry for TPD52L1: tumor protein D52-like 1,breast carcinoma associated (hD53) Gene Ontology (GO): 5 molecular function terms: About this table GO ID Qualified GO term Evidence PubMed IDs GO:0005515 protein binding IPI 12963375 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process -- -- GO:0042802 identical protein binding IPI 9484778 GO:0042803 protein homodimerization activity IDA 9484778 GO:0046982 protein heterodimerization activity IDA 9484778 [IMAGE] Find genes that share ontologies with TPD52L1 About GenesLikeMe Phenotypes: 3 GenomeRNAi human phenotypes for TPD52L1: Decreased NANOG protein expres Decreased OCT4 protein express Decreased POU5F1-GFP protein e Animal Models: [IMAGE] inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TPD52L1 [IMAGE] inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TPD52L1 [IMAGE] genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TPD52L1 [IMAGE] genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TPD52L1 miRNA Products: miRTarBase miRNAs that target TPD52L1: hsa-mir-335-5p (MIRT018898) [IMAGE] Block miRNA regulation of human, mouse, rat TPD52L1 using miScript Target Protectors [IMAGE] 2 qRT-PCR Assays for microRNAs that regulate TPD52L1: hsa-miR-513b hsa-miR-302f [IMAGE] SwitchGear 3'UTR luciferase reporter plasmid: TPD52L1 3' UTR sequence Inhib. RNA Products: [IMAGE] OriGene RNAi products in human, mouse, rat for TPD52L1 [IMAGE] Predesigned siRNA for gene silencing in human, mouse, rat TPD52L1 Gene Editing Products: [IMAGE] DNA2.0 Custom Protein Engineering Service for TPD52L1 Clone Products: [IMAGE] OriGene clones in human, mouse for TPD52L1 (see all 23) OriGene ORF clones in mouse, rat for TPD52L1 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling [IMAGE] GenScript: all cDNA clones in your preferred vector (see all 4): TPD52L1 (NM_001003396) [IMAGE] Sino Biological Human cDNA Clone for TPD52L1 [IMAGE] DNA2.0 Custom Codon Optimized Gene Synthesis Service for TPD52L1 [IMAGE] Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TPD52L1 Cell Line Products: [IMAGE] GenScript Custom overexpressing Cell Line Services for TPD52L1 [IMAGE] ESI BIO PureStem Progenitor for TPD52L1: [IMAGE] PureStem ES-210, Ecto-ntu Progenitor In Situ Assay Products: [IMAGE] Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TPD52L1
  • Similarity:
    Belongs to the TPD52 family [IMAGE]
  • Protein Domain/Family    
    Source ID Domain Name Type
    InterProIPR007327TPD52Tumor protein D52Family
    BlocksIPB007327Tumor protein D52Tumor protein D52

    Gene Ontology    
    Type Term Evidence Source Pub
    Biological Process G2/M transition of mitotic cell cycle IDA GOA 16112108
    positive regulation of JNK cascade IDA GOA 14761963
    positive regulation of MAP kinase activity IDA GOA 14761963
    regulation of cysteine-type endopeptidase activity involved in apoptotic process IDA GOA 14761963
    Cellular Component cytoplasm IDA GOA 12963375
    perinuclear region of cytoplasm IDA GOA 12963375
    Molecular Function identical protein binding IPI GOA 9484778
    protein binding IPI GOA 12963375
    protein heterodimerization activity IDA GOA 9484778
    protein homodimerization activity IDA GOA 9484778

    TPD52L1 cross reference    
    PubMed OMIM Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene