Gene content    
TTC4 ( by HUGO)
Tetratricopeptide Repeat Domain 4
Tumor suppressor gene
Tetratricopeptide Repeat Domain 4
TPR Repeat Protein 4
Tetratricopeptide Repeat Protein 4
NCBI: 1p32.3    Ensembl: 1p32.3
TTC4_HUMANSize: 387 amino acidsMass: 44679 Da

  • Function:
    Genatlas biochemistry entry for TTC4: tetratricopeptide-repeat containing gene isoform 4,ubiquitously expressed,localized within critical region,deleted in sporadic breast cancer Gene Ontology (GO): 1 molecular function term: About this table GO ID Qualified GO term Evidence PubMed IDs GO:0005515 protein binding -- -- [IMAGE] Find genes that share ontologies with TTC4 About GenesLikeMe Phenotypes: 3 GenomeRNAi human phenotypes for TTC4: Decreased POU5F1-GFP protein e Decreased number of cells in m Increased cell death in HCC-19 Animal Models: [IMAGE] inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TTC4 [IMAGE] inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TTC4 [IMAGE] genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TTC4 [IMAGE] genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TTC4 miRNA Products: [IMAGE] Block miRNA regulation of human, mouse, rat TTC4 using miScript Target Protectors [IMAGE] Selected qRT-PCR Assays for microRNAs that regulate TTC4 (see all 9): hsa-miR-647 hsa-miR-1321 hsa-miR-3166 hsa-miR-1205 hsa-miR-1207-3p hsa-miR-145 hsa-miR-802 hsa-miR-216a [IMAGE] SwitchGear 3'UTR luciferase reporter plasmid: TTC4 3' UTR sequence Inhib. RNA Products: [IMAGE] OriGene RNAi products in human, mouse, rat for TTC4 [IMAGE] Predesigned siRNA for gene silencing in human, mouse, rat TTC4 Gene Editing Products: [IMAGE] DNA2.0 Custom Protein Engineering Service for TTC4 Clone Products: [IMAGE] OriGene clones in human, mouse for TTC4 (see all 7) OriGene ORF clones in mouse, rat for TTC4 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling [IMAGE] GenScript: all cDNA clones in your preferred vector: TTC4 (NM_004623) [IMAGE] Browse Sino Biological Human cDNA Clones [IMAGE] DNA2.0 Custom Codon Optimized Gene Synthesis Service for TTC4 [IMAGE] Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TTC4 Cell Line Products: [IMAGE] GenScript Custom overexpressing Cell Line Services for TTC4 [IMAGE] Browse ESI BIO Cell Lines and PureStem Progenitors for TTC4 [IMAGE] In Situ Assay Products: [IMAGE] Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TTC4
  • Similarity:
    Belongs to the TTC4 family
                          
    Contains 3 TPR repeats [IMAGE]
  • Protein Domain/Family    
    Source ID Domain Name Type
    InterProIPR011990TPR-like_helicalTetratricopeptide-like helicalDomain

    TTC4 cross reference    
    PubMed OMIM Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene