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Subunit: Weakly associates with the oligosaccharyl transferase (OST) complex which contains at least RPN1/ribophorin I, RPN2/ribophorin II, OST48, DAD1, and either STT3A or STT3B (By similarity)
Tissue specificity: Expressed in most non-lymphoid cells and tissues examined, including prostate, lung, liver, colon, heart, kidney and pancreas [IMAGE] Custom PCR Arrays for TUSC3 Primer Products: [IMAGE] OriGene qPCR primer pairs and template standards for TUSC3 OriGene q
Function: UniProtKB/Swiss-Prot Summary: TUSC3_HUMAN, Q13454 Function: Magnesium transporter. May be involved in N-glycosylation through its association with N-oligosaccharyl transferase Gene Ontology (GO): 2 molecular function terms: About this table GO ID Qualified GO term Evidence PubMed IDs GO:0004579 contributes to dolichyl-diphosphooligosaccharide-protein glycotransferase activity ISS -- GO:0015095 magnesium ion transmembrane transporter activity IMP 19717468 [IMAGE] Find genes that share ontologies with TUSC3 About GenesLikeMe Phenotypes: 1 GenomeRNAi human phenotype for TUSC3: Increased S DNA content Animal Models: [IMAGE] inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TUSC3 [IMAGE] inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TUSC3 [IMAGE] genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TUSC3 [IMAGE] genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TUSC3 miRNA Products: miRTarBase miRNAs that target TUSC3: hsa-mir-1229-3p (MIRT036380), hsa-mir-128-3p (MIRT022014), hsa-mir-26b-5p (MIRT029507), hsa-mir-25-3p (MIRT050240) [IMAGE] Block miRNA regulation of human, mouse, rat TUSC3 using miScript Target Protectors [IMAGE] Selected qRT-PCR Assays for microRNAs that regulate TUSC3 (see all 45): hsa-miR-2052 hsa-miR-520e hsa-miR-302d hsa-miR-520f hsa-miR-605 hsa-miR-30d hsa-miR-3122 hsa-miR-372 [IMAGE] SwitchGear 3'UTR luciferase reporter plasmid: TUSC3 3' UTR sequence Inhib. RNA Products: [IMAGE] OriGene RNAi products in human, mouse, rat for TUSC3 [IMAGE] Predesigned siRNA for gene silencing in human, mouse, rat TUSC3 Gene Editing Products: [IMAGE] DNA2.0 Custom Protein Engineering Service for TUSC3 Clone Products: [IMAGE] OriGene clones in human, mouse for TUSC3 (see all 11) OriGene ORF clones in mouse, rat for TUSC3 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling [IMAGE] GenScript: all cDNA clones in your preferred vector (see all 2): TUSC3 (NM_178234) [IMAGE] Sino Biological Human cDNA Clone for TUSC3 [IMAGE] DNA2.0 Custom Codon Optimized Gene Synthesis Service for TUSC3 [IMAGE] Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TUSC3 Cell Line Products: [IMAGE] GenScript Custom overexpressing Cell Line Services for TUSC3 [IMAGE] Browse ESI BIO Cell Lines and PureStem Progenitors for TUSC3 [IMAGE] In Situ Assay Products: [IMAGE] Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TUSC3
Similarity: Belongs to the OST3/OST6 family Contains 1 thioredoxin domain [IMAGE]
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