Gene content    
WNT2B ( by HUGO)
Wingless-Type MMTV Integration Site Family, Member
Other
Wingless-Type MMTV Integration Site Family
Member 2B
WNT13
XWNT2
Xenopus
Homolog Of
Member 13
Wingless-Type MMTV Integration Site Family
Protein Wnt-2b
Wingless-Type MMTV Integration Site Family
Member 13
XWNT2
Xenopus
Homolog Of
Protein Wnt-13
NCBI: 1p13    Ensembl: 1p13.2
WNT2B_HUMANSize: 391 amino acidsMass: 43770 Da

  • Tissue specificity: Isoform 1 is expressed in adult heart, brain, placenta, lung, prostate, testis, ovary, small intestine and colon. In the adult brain, it is mainly found in the caudate nucleus, subthalamic nucleus and thalamus. Also detected in fetal brain, lung and kidne
  • Function:
    UniProtKB/Swiss-Prot Summary: WNT2B_HUMAN, Q93097 Function: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. May be involved in normal development or differentiation as well as in carcinogenesis
  • Similarity:
    Belongs to the Wnt family [IMAGE]
  • Protein Domain/Family    
    Source ID Domain Name Type
    InterProIPR005817WntWnt superfamilyFamily
    IPR009140Wnt2Wnt-2 proteinFamily
    BlocksIPB005816Secreted growth factor Wnt proteinSecreted growth factor Wnt protein

    Gene Ontology    
    Type Term Evidence Source Pub
    Biological Process chondrocyte differentiation IEP GOA 15135146
    cornea development in camera-type eye ISS GOA 16258938
    forebrain regionalization IEP GOA 15164427
    hematopoietic stem cell proliferation IDA GOA 9787155
    iris morphogenesis ISS GOA 16258938
    lens development in camera-type eye ISS GOA 16258938
    male gonad development IEP GOA 17848411
    positive regulation of canonical Wnt signaling pathway IDA GOA 11741304
    Wnt signaling pathway IMP GOA 15135146
    Cellular Component extracellular space NAS GOA 15135146

    WNT2B cross reference    
    PubMed OMIM Entrez Gene NCKU SNP Nucleotide UniProt Genome Data Viewer HomoloGene