|B.S. National Cheng-Kung University||1982-1986|
|M.S. Eastern Michigan University||1990-1992|
|Ph.D. University of Wisconsin-Madison||1993-1997|
|Joined Cheng Kung University Faculty||1998|
|Visiting Professor, Baylor College of Medicine||2010-2011|
|Director General, Ministry of Science and Technology||2014-2017|
|Ambassador, World Endometriosis Society||2014-|
|President, The Chinese Physiological Society||2016-|
|Councilor, Society for Experimental Biology and Medicine||2018-|
|President, Asian Society for Endometriosis and Adenomyosis||2019-|
|Education and Experience:|
Office: +886-6-2353535 ext.5426
82-0701 Basic Medical Science Building
Endometriosis is a common gynecological disease with the prevalence of 10-15 %. It is a complex disease with unknown etiology and severely reduces life quality of affected women and their family. We focus on local and epigenetic factors that cause inflammation in the peritoneal cavity, aberrant production of steroid hormones, angiogenesis, and suppression of immune function.
Drug resistance is the most critical issue that contributes to treatment failure and mortality. Hypoxia is one of the most critical factors contributing to drug resistance. However, mechanisms responsible for hypoxia-mediated increased in drug resistance remain largely unknown. We have employed systems biology approach to investigate effects of hypoxia-mediated gene regulatory networks in drug resistance and cancer malignancy.